The divided Syrian city of Aleppo has seen a morning of air attacks, with reports of barrel bombs hitting a hospital already bombed this week.
The Russian and Syrian air forces have been attacking the rebel-held east of the city, causing international outrage at the mounting civilian death toll.
Government forces began a ground offensive against the rebels more than a week ago as a truce collapsed.
The US says Russia is driving moderate rebels into the arms of jihadists.
Once Syria's commercial and industrial hub, Aleppo has been divided roughly in two since 2012.
The UN says at least 400 civilians, including many children, have been killed in the city this week as a result of Russian and Syrian government attacks.
Rebel shelling has also claimed civilian lives in the east, reports say.
Hospital hit
A spokesman for the Syrian American Medical Society, a non-governmental organisation, told AFP news agency two barrel bombs - improvised devices dropped from helicopters - had hit a hospital it supports.
"There were reports of a cluster bomb as well," Adham Sahloul said.
The M10 hospital was said to be out of service after it was bombarded on Wednesday but one report suggests patients were still being treated there on Saturday.
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